Spatial compartmentalization of signal transduction in insulin action
Spatial compartmentalization of signal
transduction in insulin action
Christian A. Baumann and Alan R. Saltiel*
Summary
Insulin resistance is thought to be the primary defect in
the pathophysiology of type 2 diabetes. Thus, under-
standing the cellular mechanisms of insulin action may
contribute significantly to developing new treatments for
this disease. Although the effects of insulin on glucose
and lipid metabolism are w
