手术组（14.12±4.13）mmHg, the difference was statistically significant (P<0.05). The postoperative ICP in the early surgery group showed a trend of slowly increasing and then decreasing, with higher values on the 3rd and 5th days after surgery compared to the 1st day, reaching its peak on the 5th day, and then dropping below the 1st day's value on the 7th day, with statistical significance (P<0.05). In contrast, for the delayed surgery group, ICP increased on the 2nd day postoperatively and then declined, with lower averages on the 6th and 7th days compared to the 1st day, with the 7th day being the lowest, also showing statistical significance (P<0.05). No significant difference was found in the average ICP on the 7th day between the two groups (P>0.05).
Conclusion: Ruptured cerebral aneurysm patients undergoing surgery within 3 days of onset generally have higher postoperative ICP compared to those who had delayed surgery. Both early and delayed surgeries exhibit a pattern of initially rising ICP followed by a decline, with the peak occurring on the 5th day for early surgery and the 2nd day for delayed surgery. After treatment, ICP in both groups could be reduced to a lower level. This pattern provides insight into the management strategies for elevated ICP in patients after ruptured cerebral aneurysm surgery.
This study highlights the importance of monitoring ICP in patients following different timing of ruptured brain aneurysm clipping surgeries. It suggests that while early intervention might lead to higher initial ICP, it is also associated with a subsequent decline, similar to the delayed surgery group. The findings emphasize the need for tailored treatment plans based on the timing of the surgical intervention to optimize patient outcomes. The 12-month follow-up results, as measured by mortality and mRS scores, did not reveal significant differences between the two groups, indicating that both surgical approaches may have comparable long-term effects.
The research findings underscore the significance of ICP monitoring in guiding the care of patients with ruptured cerebral aneurysms. By understanding the temporal changes in ICP following different surgical timings, healthcare professionals can better manage patient care, potentially reducing complications and improving recovery. Future studies could delve deeper into the factors influencing these ICP dynamics and explore more targeted interventions to further optimize outcomes.
In summary, this study contributes to the body of knowledge in the field of neurosurgery by investigating the ICP dynamics in patients who underwent ruptured brain artery aneurysm clipping at different time points. It emphasizes the importance of early intervention, even though it may temporarily result in higher ICP, as both early and delayed surgeries demonstrate a similar downward trend in ICP over time. These findings have implications for the development of individualized treatment plans and the optimization of postoperative care in managing patients with this critical condition.
