The evolution of dosage-compensation mechanisms
The evolution of dosage-compensation
mechanisms
Ignacio MarõÂn,1 Mark L. Siegal,2 and Bruce S. Baker2*
Summary
Dosage compensation is the process by which the
expression levels of sex-linked genes are altered in one
sex to offset a difference in sex-chromosome number
between females and males of a heterogametic species.
Degeneration of a sex-limited chromosome to produce
heterogamety is a common, perhaps unavoidable, feature
of sex-chromosome ev
