ICP0, a regulator of herpes simplex virus during lytic and laten...

ICP0, a regulator of herpes simplex virus during lytic and latent infection ICP0, a regulator of herpes simplex virus during lytic and latent infection Roger D. Everett Summary Cold sores produced by HSV-1 infection are an annoy- ing but trivial recurrent problem for most of us, but the virus can also cause more serious disease. Episodes of active HSV-1 infection, in response to stress or sunlight, are possible because the virus establishes a latent infection in neurones which can not be elim