Histone acetylation and an epigenetic code
Histone acetylation and
an epigenetic code
Bryan M. Turner
Summary
The enzyme-catalyzed acetylation of the N-terminal tail
domains of core histones provides a rich potential
source of epigenetic information. This may be used both
to mediate transient changes in transcription, through
modification of promoter-proximal nucleosomes, and
for the longer-term maintenance and modulation of
patterns of gene expression. The latter may be achieved
by setting s
