In this Issue
T h e J o u r n a l o f
G E N E M E D I C I N E
In this Issue
Triplex-forming molecules –
a review
Molecules that recognize specific
sequences on the DNA double helix
provide interesting tools for interfering
with DNA information processing at an
early stage of gene expression. Triplex-
forming molecules (TFMs) specifically
recognize oligopyrimidine/oligopurine
sequences by hydrogen bonding inter-
actions. In this extensive review, Faria
and Giovannangeli outline the bases of
