Jerman增强滤波器 可行.zip_Hessian 滤波器_Jerman_hessian增强_血管增强_血管滤波器

# Jerman Enhancement Filter Jerman's 3D and 2D Hessian based tubular (vessel/vesselness) and spherical (blob/blobness) enhancement filters. The MATLAB code is the implementation of the next two journal publications: 1. [T. Jerman, F. Pernus, B. Likar, Z. Spiclin, "*Enhancement of Vascular Structures in 3D and 2D Angiographic Images*", IEEE Transactions on Medical Imaging, 35(9), p. 2107-2118 (2016), doi={10.1109/TMI.2016.2550102}](https://doi.org/10.1109/TMI.2016.2550102) 2. [T. Jerman, F. Pernus, B. Likar, Z. Spiclin, "*Blob Enhancement and Visualization for Improved Intracranial Aneurysm Detection*", IEEE Transactions on Visualization and Computer Graphics, 22(6), p. 1705-1717 (2016), doi={10.1109/TVCG.2015.2446493}](https://doi.org/10.1109/TVCG.2015.2446493) and a conference paper (please refer to journal publication [1] for more details): 3. [T. Jerman, F. Pernus, B. Likar, Z. Spiclin, "*Beyond Frangi: an improved multiscale vesselness filter*", Proc. SPIE 9413, Medical Imaging 2015: Image Processing, 94132A (2015), doi={10.1117/12.2081147}](https://doi.org/10.1117/12.2081147) The code is based on Dirk-Jan Kroon's implementation of Frangi's vesselness filter. (https://www.mathworks.com/matlabcentral/fileexchange/24409-hessian-based-frangi-vesselness-filter) ### Tips: * Make sure that the objects of interest have the highest (if bright compared to the background) or lowest (if dark compared to background) intensities in the image/volume. Scale/normalize the images appropriately. * The 3D method contains a c-code file that needs to be compiled with "mex eig3volume.c". (For more info visit: https://www.mathworks.com/matlabcentral/fileexchange/24409-hessian-based-frangi-vesselness-filter) * Threshold the filter response to remove any remaining enhanced noise ### Content: 2D enhancement of vessel/tube-like structures: * vesselness2D.m - main function * example_vesselness2D.m - filter applied on a 2D retinal vasculature * fundus2D.png - image for the example 3D enhancement of vessel/tube-like structures: * vesselness3D.m - main function * eig3volume.c - fast computation of eigenvalues * example_vesselness3D.m - filter applied on a 3D cerebral vasculature * volume.mat - volume for the example 3D enhancement of blob/sphere-like structures: * blobness3D.m - main function * eig3volume.c - (as above) * example_blobness3D.m - aneurysm enhancement in a 3D cerebral vasculature * volume.mat - (as above) 2D enhancement of blob/disk-like structures (**experimental - not published**): * blobness2D.m - main function * example_blobness2D.m - enhancement of an aneurysm on a vessel (*synthetically generated image*) * blob2D.png - image for the example