ECOG 1594 � �
� � � � � � � � � � � � � � � � � �
Schiller JH, et al. N Engl J Med. 2002 Jan 10;346(2):92-8.
� � /� � � �
N=301
� � /� � �
N=303
1:1:1:1
� � � � � OS
� � � � � ORR � � � � � � � � (TTP)
• IIIB(� � � � � /� � � � )/IV� � � � � NSCLC
• � � � � � � �
• � � ≥ 18 �
• � � � � � � � � � � � � � � � � � �
• � � � � � � � � � � � � � � � � � � � � � � � � � � � �
• � � � � � � � � � � �
N=1207
7.8
3.4
8.1
4.2
7.4
3.7
8.1
3.1
OS TTP
0
1
2
3
4
5
6
7
8
9
� � /� � �
� � /� � � �
� � /� � � �
� � /� � �
OS/TTP( � )
21.0
22.0
17.0 17.0
� � /� � � � � /� � � � � � /� � � � � � /� � �
0
5
10
15
20
25
ORR(%)
� � /� � � �
N=304
� � /� � �
N=299
R
ECOG 1594 � � � � � � � 4 � � � � � � � � � � OS � TTP � ORR � �
