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D I A B E T E S / M E T A B O L I S M
R e s e a r c h a n d R e v i e w s
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T-cell response to IA-2
peptides
Schulz et al. describe T-cell reactivity
to selected peptides of the islet auto-
antigen IA-2. The population is of
particular interest since it includes
concordant and discordant twins. No
disease-associated T-cell responses to
these peptides were found. The
authors conclude that T-cell responses
to selected IA-2 peptides are not
genetically determined, he