现代生学物学期末论文-张锦程-材料-20180120821
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Introduction to Three Different Kinds of Anti-cancer
Therapies
【张锦程 材料学院 2018012082】
2019 / 10 / 22
Abstract:
In the TED videos, three different kind of anti-cancer therapies are introduced. All of them
have certain features and can complement some shortcomings of traditional methods of
treating cancers.
Antiangiogenic therapy utilizes the mechanism of human angiogenesis, by controlling this
elaborate human angiogenic system, we target at vessels that are feeding the cancer cells,
cutting off the blood and oxygen supply of them. It has a cutting edge from chemotherapy
or radiation, because it’s highly selective and won’t affect other tissues. What’s more, further
studies show that many kinds of food contain naturally antiangiogenic element, so we can
“eat to starve cancer”, and it’s able to kill cancer when it’s not dangerous.
Color-coded surgery applies fluorescent with specificity to stain tissue and color-code the
surgical field. It changes the way surgeries used to be conducted. Through the magic of
fluorescence, surgeons can see what they currently can't see, distinguish between different
tissues, detect early cancers, avoid inadvertent injury of nerves and determine whether there’s
tumors uncut after a surgery more easily. All of these will result in surgeries with a better
outcome and fewer complications.
Tumor Treating Electric Fields make use of the effect of electric field on charged protein called
Tubulin, once exerted, the cell cycle of cancer cells is disrupted, and then the cancer cells are
driven into a programmed cell death. Compared with traditional therapy, Tumor Treating
Fields have no effect on normal undividing cells, which minimize the side effects. Even better,
synergies are observed between chemotherapy, radiation and Tumor Treating Fields.
1. Antiangiogenic therapy
1.1 Brief introduction to human angiogenesis and its mechanism
Angiogenesis refers to the process that our bodies use to grow blood vessels. Typically, there’s
60,000 miles worth of vessels in an adult. End to end, that would form a line that would circle
the earth twice.
As adults, blood vessels don't normally grow except in some special circumstances like
pregnancy or injury. That’s because the body can regulate the amount of blood vessels. For
example, in conditions the number of vessels is beneath the baseline, the human body are
able to grow more blood vessels, until it get back to its normal levels.
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