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ADVIA Centaur
®
CP Immunoassay System
LIS Interface Guide
086D0004-01 Rev. A, 2005-09
© 2005 Bayer HealthCare LLC. All rights reserved.
No part of this manual or the products it describes may be reproduced by any means or in any form without
prior consent in writing from Bayer HealthCare LLC.
Bayer, the Bayer cross, ADVIA, ADVIA Centaur, and ADVIA CentraLink are trademarks of Bayer.
The information in this manual was correct at the time of printing. However, Bayer HealthCare LLC
continues to improve products and reserves the right to change specifications, equipment, and maintenance
procedures at any time without notice.
If the ADVIA Centaur CP system is used in a manner differently than specified by Bayer HealthCare LLC,
the protection provided by the equipment may be impaired. Observe all warning and hazard statements.
086D0004-01, Rev. A
Contents
1Introduction
Who Should Read this Manual . . . . . . . . . . . . . . . . . . . . . . . . . . 1-1
How this Manual is Organized. . . . . . . . . . . . . . . . . . . . . . . . . . . 1-1
Other ADVIA Centaur CP System Documents. . . . . . . . . . . . . . 1-2
Conventions Used in this Manual . . . . . . . . . . . . . . . . . . . . . . . . 1-3
2 Overview
Layered Communications Protocols . . . . . . . . . . . . . . . . . . . . . 2-1
Layers and Messages. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-2
Application Messages. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-2
Data Link Messages. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2-3
Physical Layer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2-9
Interaction Between Layers. . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-10
ASTM Application and Data Link Layer Interaction . . . . . . . . . . . . . . . 2-11
Interaction Between Layers on Incoming Messages . . . . . . . . . . . . . . 2-11
Interaction Between Layers on Outgoing Messages . . . . . . . . . . . . . .2-12
Event Log . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-13
3ASTM
Features. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-1
Operator-Initiated Transfers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-1
Remote System-Initiated Transfers . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-1
Automatic ADVIA Centaur CP System-Initiated Transfers . . . . . . . . . . .3-2
Defining LIS Communication Options. . . . . . . . . . . . . . . . . . . . . . . . . . .3-2
Requesting a Worklist from an LIS. . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-2
Sending Results to an LIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-2
Limitations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-3
Physical Layer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-3
Electrical Characteristics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-3
Signal Characteristics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-4
Data Link Layer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-4
ASTM Data Link Layer Protocol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-5
Message Transfer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-6
Link Release. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-8
Error Detection and Recovery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-8
ADVIA Centaur CP LIS Interface Guide Contents 2
086D0004-01, Rev. A
Flow Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-9
ASTM Data Link Layer Protocol Events . . . . . . . . . . . . . . . . . . . 3-9
ASTM Data Link Messages - Sender . . . . . . . . . . . . . . . . . . . . . . . . . .3-10
ASTM Data Link Messages - Receiver. . . . . . . . . . . . . . . . . . . . . . . . . 3-11
ASTM Data Link Timers - Receiver . . . . . . . . . . . . . . . . . . . . . . . . . . .3-12
ASTM Data Link Frame Limits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-12
ASTM Data Link Miscellaneous Characters. . . . . . . . . . . . . . . . . . . . .3-12
Data Link Layer Enabling and Disabling . . . . . . . . . . . . . . . . . 3-13
Application Layer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-13
Data Transfer and Processing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-13
ADVIA Centaur CP System as Data Source . . . . . . . . . . . . . . . . . . . .3-13
Selecting Data for Transfer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-14
ADVIA Centaur CP System as Data Destination . . . . . . . . . . . . . . . . . 3-15
Processing Received Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-16
Application Layer Protocol . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-17
Messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-17
ASTM Record Structure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-19
Record Data Contents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-21
Data Link Layer Interaction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-51
ASTM Protocol Exceptions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3-51
Query Timer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-51
Error Handling. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-52
4 Communication
5 Troubleshooting
Delays in Automatic Worklist Requests. . . . . . . . . . . . . . . . . . . 5-1
Possible Cause: Termination Record . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-1
Possible Cause: LIS Response to the Query . . . . . . . . . . . . . . . . . . . . . 5-2
Missing Worklist Response to a Request . . . . . . . . . . . . . . . . . 5-2
Possible Cause: Query Timeout. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-2
Invalid Test Order . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-3
Possible Cause: Disabled Test. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-3
Reject. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-4
Possible Cause: SID. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-4
Rejected Test Order for Patient Sample. . . . . . . . . . . . . . . . . . . 5-4
Possible Causes and Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-4
Test Results Transmitted with Wrong Test Name. . . . . . . . . . . 5-4
ADVIA Centaur CP LIS Interface Guide Contents 3
086D0004-01, Rev. A
Possible Cause: LIS Code . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-4
Message Received Caused Fatal Parse Error . . . . . . . . . . . . . . 5-5
Possible Cause: Carriage Return. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-5
Possible Cause: Incorrect Sequence Number . . . . . . . . . . . . . . . . . . . . 5-5
Invalid ASTM Record Type Received . . . . . . . . . . . . . . . . . . . . . 5-5
Possible Cause: Inactive Tests. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-5
Possible Cause: Transmission Interference . . . . . . . . . . . . . . . . . . . . . .5-5
Possible Cause: Carriage Return. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-6
Unexpected Data Received in Response to a Query. . . . . . . . . 5-6
Possible Cause: Query Record . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-6
Delay Between Messages Sent by the ADVIA Centaur CP System
5-8
Possible Causes and Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-8
Automatic Query is Malfunctioning . . . . . . . . . . . . . . . . . . . . . . 5-9
Possible Causes and Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-9
Automatic Result Reporting is Malfunctioning . . . . . . . . . . . . . 5-9
Possible Causes and Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-9
No Communications at All. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-10
Possible Causes and Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5-10
Appendix A: Safety Information
Protecting Yourself from Biohazards . . . . . . . . . . . . . . . . . . . . . . . . . . .A-1
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .A-2
Appendix B: Support Information
Bayer Authorized Representative . . . . . . . . . . . . . . . . . . . . . . . . B-1
Addresses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . B-1
Appendix C: Messages
Characters from the Application Layer . . . . . . . . . . . . . . . . . . . C-1
Automatic Worklist Request and Response for a Patient Sample . . . . .C-1
Automatic Worklist Request and Response with No Demographic or
Pending Test Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .C-2
Manual Worklist Request and Response with No Demographic or Pending
Test Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .C-2
Manually Initiated Worklist Query With Demographic and Assay Response
C-3
LIS Cancellation of a Scheduled Test. . . . . . . . . . . . . . . . . . . . . . . . . . .C-3
剩余127页未读,继续阅读
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