The tumor suppressor Sprouty2 is directly regulated by miR-21 and miR-27a in human hepatocellular carcinoma

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微小RNA miR-21和miR-27a调控抑癌基因Sprouty2在肝癌中的表达,丁洁,黄胜林,Sprouty2基因是Ras/ERK通路抑制剂,在很多肿瘤中下调,但为何下调的机理还不清楚。本文发现两个微小RNA miR-21和miR-27a可直接调控Sprouty2在�

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