论文研究 - 间质性肺异常的定量CT指数和CT视觉评分是并发肺癌的指标
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Open Journal of Radiology, 2019, 9, 105-114
http://www.scirp.org/journal/ojrad
ISSN Online: 2164-3032
ISSN Print: 2164-3024
DOI:
10.4236/ojrad.2019.92010 May 6, 2019 105 Open Journal of Radiology
Quantitative CT Indexes and CT Visual Score in
Interstitial Lung Abnormality as Indicators of
Concurrent Lung Cancer
Akihiro Hotta
1*
, Kazuhiro Suzuki
1
, Mariko Fukui
2
, Katsutoshi Ando
3
,
Kenji Suzuki
2
, Ryohei Kuwatsuru
1
, Kazuya Takamochi
2
1
Departments of Radiology, Faculty of Medicine, Juntendo University, Tokyo, Japan
2
Departments of Thoracic Surgery, Faculty of Medicine, Juntendo University, Tokyo, Japan
3
Departments of Respiratory Medicine, Faculty of Medicine, Juntendo University, Tokyo, Japan
Abstract
Background:
The associations between the severity of interstitial lung disease
and the stage and histologic type of concurrent lung cancer remain unknown.
Purpose:
To evaluate whether the severity of interstitial lung abnormality
(ILA), as indicated by quantitative computed tomographic (CT) indexes and
CT visual score, was correlated with the stage and histological type of con-
current lung cancer.
Materials and Methods:
Twenty-
eight patients with
surgically diagnosed lung cancer and ILA on CT were enrolled in this retros-
pective study. The subjects were allocated to one of three groups by histolog-
ical type: adenocarcinoma group (13 subjects); squamous cell carcinoma
group (10 subjects); and the
other histological diagnosis group (5 subjects).
Two independent observers evaluated
the CT findings to determine the CT
visual score, and the kurtosis and skewness of CT-
based density histograms
were determined. The relationships between severity of ILA and the patho-
logical stage and histological type of concurrent lung cancer were evaluated.
Results:
There were no significant differences in the CT visual scores and
quantitative indexes among the three groups. CT visual score was significant-
ly negatively correlated with pathological stage (
r
= −0.43,
P
= 0.025).
Con-
clusion:
Patients can have only mild ILA on visual scoring but advanced lung
cancer. Therefore, the frequency of follow-
up examination should not be
based on the severity of ILA on CT.
Keywords
CT Visual Score, Interstitial Lung Disease, Lung Cancer, Quantitative CT Index
How to cite this paper:
Hotta, A., Suzuki,
K
., Fukui, M., Ando, K., Suzuki, K., Ku-
watsuru
, R. and Takamochi, K. (2019
)
Quantitative CT Indexes and CT Visual
Score in Interstitial Lung Abnormality as
Indicators of Concurrent Lung Cancer.
Open Journal of Radiology
,
9
, 105-114.
https://doi.org/10.4236/ojrad.2019.92010
Received:
April 11, 2019
Accepted:
May 3, 2019
Published:
May 6, 2019
Copyright © 201
9 by author(s) and
Scientific
Research Publishing Inc.
This work is licensed under the Creative
Commons Attribution International
License (CC BY
4.0).
http://creativecommons.org/licenses/by/4.0/
Open Access
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